Wichtige Publikationen

 

Lehr- und Forschungsgebiet Biochemie und Molekulare Immunologie

  1. Zorn CN, Pardo J, Martin P, Kuhny M, Simon MM, Huber M. Secretory lysosomes of mouse mast cells store and exocytose active caspase-3 in a strictly granzyme B-dependent manner. Eur. J. Immunol. 2013; 43: 3209-18.
  2. Fehrenbach K, Lessmann E, Zorn CN, Kuhny M, Grochowy G, Krystal G, Leitges M, Huber M. Steel Factor enhances supra-optimal antigen-induced interleukin-6 production from mast cells via activation of protein kinase C-b. J. Immunol. 2009; 182: 7897-905.
  3. Ali S, Huber M, Kollewe C, Bischoff SC, Falk W, Martin MU. The interleukin-1 receptor accessory protein is essential for interleukin-33 induced activation of T cells and mast cells. Proc. Natl. Acad. Sci. U. S. A. 2007; 104: 18660-5.
  4. Huber M, Kalis C, Keck S, Jiang Z, Georgel P, Du X, Shamel L, Sovath S, Mudd S, Beutler B, Galanos C, Freudenberg M. R-form LPS, the master key to the activation of TLR4/MD2 positive cells. Eur. J. Immunol. 2006; 36: 701-11.
  5. Kalesnikoff J, Huber M, Damen JE, Bigg CM, Lam V, Siraganian R, Krystal G. Monomeric IgE stimulates signaling pathways in mast cells that lead to cytokine production and cell survival. Immunity 2001; 14: 801-11.